Center of the design
01
Dopaminergic signaling
Modulated by the ECS through CB1 receptors. The pathway at the center of Solenva's design.
The Science
Your body already runs a balance system.
The endocannabinoid system is the body's primary regulatory network. It governs mood, sleep, and muscle tone, and it modulates the dopamine pathway. Solenva™ delivers the Phyto-38 Complex™ to support it.
2M+
cannabinoid combinations screened
CB1 · CB2
receptors engaged
73%
of surveyed users reported improvement
8 of 8
daily-life domains improved
How it works
From receptor to daily function.
Three steps, from the system itself to the way Solenva™ engages it.
Step 01 · Endocannabinoid system
The body's own regulatory network.
The endocannabinoid system is the body's primary regulatory network. Its CB1 and CB2 receptors are distributed throughout the central and peripheral nervous system, where they help govern mood, sleep, stress, and muscle tone. It holds these in balance through what is called endocannabinoid tone.
Step 02 · Dopaminergic modulation
Where the ECS meets dopamine.
The endocannabinoid system modulates dopaminergic signaling through CB1 receptors in the striatum and basal ganglia. Supporting ECS function supports the dopamine pathway. This connection is the mechanism at the center of Solenva's design.
Step 03 · Selective engagement
Support, without overstimulation.
The Phyto-38 Complex™ engages the same CB1 and CB2 receptors your body already uses, without overstimulating them. It was investigated for dopamine secretion in neuronal cell models, then graduated to early user-experience testing.
When tone drifts
What you may notice.
When endocannabinoid tone is under-supported, the systems it regulates are the first to show it.
Signal · off baseline
01
Physical tension that compounds.
Muscle rigidity that holds through the night and into the morning. Stiffness that makes simple movements cost more than they should.
The ECS helps regulate muscle tone.
02
Focus that breaks at the wrong moment.
Concentration that costs more effort than it should. Emotional weight that sits alongside everything else.
The ECS governs mood and cognition.
03
A nervous system that never fully settles.
Sleep that does not fix the fatigue. Days when steadiness, physical and emotional, feels out of reach.
The ECS influences circadian rhythm, sleep duration, and the return to baseline.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The mechanism, in motion
Signaling that finds its baseline.
Endocannabinoid tone is built through repetition. Each day reinforces the baseline and moves the system toward homeostasis.
Five pathways
What the Phyto-38 Complex™ supports.
One complex, built to support the endocannabinoid system across the pathways it regulates.
02
Endocannabinoid tone
The balance the ECS maintains. The Phyto-38 Complex™ is built to support it.
03
Neuromuscular comfort
Muscle-tone regulation. The highest-burden domain, and the largest average improvement in early testing.
04
Mood & cognition
Emotional steadiness and daily concentration, governed by the ECS.
05
Sleep & recovery
Circadian rhythm and the body's return to a stable baseline.
How Phyto-38™ was discovered
Two million screened. One selected.
Phyto-38™ emerged from screening millions of combinations. Four steps, from the pathway to the people.
01
Map the pathway
Start from the endocannabinoid system and its role in dopaminergic signaling.
02
Screen the space
Evaluate a combinatorial space of over two million cannabinoid combinations.
03
Isolate Phyto-38™
The combination with the most consistent, reproducible dopaminergic support profile.
04
Verify with people
Graduate the complex to early user-experience testing across daily-life domains.
The evidence
Measured across daily life.
Directional, self-reported improvement from early user-experience testing of the Phyto-38 Complex™.
What early users reported
A noticeable improvement in how they felt, day to day.
Early user survey of Phyto-38 Complex™. About 2 in 3 of 13 participants reported a noticeable improvement. Self-reported. Individual experiences vary.
Daily-life domains
Directional, self-reported improvement across the domains measured.
Muscle comfortBiggest gain
Emotional wellbeing
Concentration
Sleep quality
Physical comfort
Social confidence
8 of 8 daily-life and 13 of 13 motor measures improved on average; none worsened. Directional, self-reported. Early user testing. Results may vary.
Phyto-38 Complex™
The science, in a daily protocol.
Daily support for your endocannabinoid system and the dopamine pathway it helps regulate.
Start your 90 day protocol →Notes & methodology
Survey figures reflect a user survey of Phyto-38 Complex™ (N=13): self-reported. Individual experiences vary. Domain figures are directional.
This page is educational and is not medical advice. Solenva™ is a dietary supplement, not a medication. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.